ea0020s19.3 | Bone endocrinology | ECE2009
Manolagas Stavros
In contrast to traditional ideas that loss of estrogens at menopause is the seminal mechanism of osteoporosis, bone loss begins as early as the early part of the third decade in both women and men; substantial trabecular bone loss occurs in sex steroid sufficient young adult women and men; and after the first few years of accelerated bone loss in postmenopausal women, bone mass and strength decline in both sexes at the same rate. Consistent with these clinical observations, me...